Tires April 28, 2019, 07:36:00 pm Is there a big difference between a truck tire and an RV tire. Friend of mine just got four new truck tires 275 80R 22.5 for about $300, the RV tire was anywhere from $400 to $600. He says they ride great and are quirt etc. I will be shopping for 6 tires in the near future. I have the FMCA Michelin tire advantage program.